Hacham Yoseph Faladji was born to Esterolla and Hacham Haim Faladji in 1815 in Izmir, Turkey. He learned Torah from his father, Hacham Bashi and chief head of the Rabbinic Courts of Izmir, and his eldest brother, Hacham Abraham Faladji, who eventually replaced their father as Rabbi of Izmir after his death in 1869.
Hacham Yoseph Faladji jointly authored VaYosesf Et Avraham with his brother, Hacham Abraham Faladji, on the attributes of Joseph the Righteous published in 1881, and VaYosef Et Ekhav, on Talmudic topics, published in 1896. His son, Hacham Binyamin Faladji, had She'erit Yosef, his last book of original commentary, published.
Hacham Yoseph Faladji passed away on 12 Tammuz 5656 (1896) and was buried in Izmir.