Hacham Yaacov Sukari, was born to Sarah, Hacham Yaacov Entebbe's daughter, and Hacham Shlomo in the city of Damascus.
As a young man, he studied Torah with his father and then studied in Hacham Meir Lisbona's Beit Midrash, along with Hacham Nissim Bokai and Hacham David Pinto.
Hacham Yaacov Sukari married Serach Mizrachi, and the couple had four children.
Hacham Yaacov Sukari, following his father's custom, would rise at midnight to study Torah.
After his mother died in 1875 he began to encounter financial difficulties and had to leave Damascus. He reached Egypt in 1879, where he had his book Vaykra Ya'acov printed. In 1882 he travelled to Calcutta and Bombay, where he had his book Yoru Mishpatecha Le'Ya'acov printed.
Towards the end of his life, he succeeded in immigrating to the Land of Israel.
Hacham Yaacov Sukaru passed away on 6 Shevat, 5668 (1908). He authored the following books: Vayikra Ya'acov – on the weekly Torah reading portions, Yoru Mishpatecha LeYa'acov – morals on Torah and work, and Vayehi Ya'acov – a commentary on the Book of Psalms.